Karyopharm Therapeutics Inc.

Address : 85 Wells Avenue, Newton, Massachusetts 02459, United States

Industries : Pharmaceuticals, Research, Hospital & Health Care, Biotechnology

Company Description

Karyopharm Therapeutics Inc. (Nasdaq: KPTI) is an innovation-driven pharmaceutical company dedicated to the discovery, development, and commercialization of novel first-in-class drugs directed against nuclear export and related targets for the treatment of cancer and other major diseases. Karyopharm's Selective Inhibitor of Nuclear Export (SINE) compounds function by binding with and inhibiting the nuclear export protein XPO1 (or CRM1). Karyopharm's lead compound, XPOVIO® (selinexor), received accelerated approval from the U.S. Food and Drug Administration (FDA) in July 2019 in combination with dexamethasone as a treatment for patients with heavily pretreated multiple myeloma. In June 2020, XPOVIO was approved by the FDA as a treatment for patients with relapsed or refractory diffuse large B-cell lymphoma. A Marketing Authorization Application for selinexor for patients with heavily pretreated multiple myeloma is also currently under review by the European Medicines Agency. In addition to single-agent and combination activity against a variety of human cancers, SINE compounds have also shown biological activity in models of neurodegeneration, inflammation, autoimmune disease, certain viruses and wound-healing. Karyopharm has several investigational programs in clinical or preclinical development.

Specialities

Oncology
Biotech
Lymphoma
Glioblastoma
Clinicaltrials
Drugdiscovery
Healthcare
Life Sciences
Hospital & Health Care
Pharmaceutical Manufacturing
Health, Wellness & Fitness

Pharmaceutical
Multiplemyeloma
Solidtumors
Clinicalresearch
Research
Medical
Biotechnology
Pharmaceuticals
Diversified Commercial Services
Health Care

Financial

Employees Total : 420

Revenue (Yearly) : 146M

Total Funding : 343.3M

Latest Funding : 165M

Public Company : Yes

Trade Symbol : KPTI

Trade Exchange : Nasdaq

Market Cap : 146M

Miscellaneous

Founded in : 2008

Twitter : Karyopharm

Facebook : KaryopharmTherapeutics

Linkedin : karyopharm

Angellist : angel.co/karyopharm-therapeutics

Customer Relationship Management : Salesforce

Email Providers : Mimecast

Tech : Microsoft Office 365

Hosting : Google Cloud Hosting

CMS : BuddyPress

CMS : Atlassian Cloud

Last Updated : 2023-12-21

Jobs Vacancies

Medical Director
United States
Posted at : 2023-12-14

Senior Medical Science Liaison - Southern CA, AZ
California, United States
Posted at : 2023-11-03

Employees

Dan Lewycky ( Head of Commercial Operations )
Casey Kemp ( Associate Director of Workplace Services )
Alex Ragno ( Senior Manager, Commercial Finance )
Brian Austad ( Senior Vice President, Pharmaceutical Sciences )

Andy Holton ( Associate Vice President, Market Access )
Frances Wong ( Director, Formulation Development )
Christopher Gustavsen ( IT Support Specialist )

Alumni

Amir Hafeez ( Senior Medical Director )
Bon Lam ( Senior Clinical Compliance Specialist - Contract role )
Bruce Warren ( Clinical Data Analyst )
Brian Floyd ( Senior Clinical Contracts Manager )
Benjamin Smith ( Project Manager - Commercial Effectiveness & Training )

Adam Yakovich ( Global Lead, Myeloma Development Program/Director, Medical Affairs )
Connor Hayes ( TMF Coordinator )
Brittany Eisenbarth Jenkins ( Associate Director, Data Management )
Alexandra Gavrilovic ( eTMF Coordinator )